Pyridines and derivatives
Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.
Quantity
- (4)
- (1)
- (5)
- (5)
- (520)
- (22)
- (2,105)
- (22)
- (2)
- (5)
- (5)
- (271)
- (175)
- (1)
- (14)
- (50)
- (300)
- (86)
- (225)
- (6)
- (4)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (12)
- (4)
- (8)
- (7)
- (12)
- (60)
- (867)
- (5)
- (55)
- (60)
- (58)
- (19)
- (346)
- (2)
- (4)
- (2)
- (1)
- (1)
- (5)
- (275)
- (1)
- (1,700)
- (2)
- (27)
- (7)
- (1)
- (92)
- (4)
- (13)
- (77)
- (128)
- (54)
- (59)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
Molecular Weight (g/mol)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (9)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (5)
- (17)
- (23)
- (1)
- (1)
- (60)
- (21)
- (1)
- (1)
- (29)
- (49)
- (7)
- (2)
- (1)
- (5)
- (6)
- (12)
- (1)
- (1)
- (1)
- (18)
- (1)
- (14)
- (4)
- (1)
- (11)
- (5)
- (1)
- (10)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (9)
- (7)
- (1)
- (2)
- (1)
- (4)
- (6)
- (2)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (1)
- (5)
- (15)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (15)
- (17)
- (4)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (5)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (16)
- (7)
- (5)
- (1)
- (1)
- (3)
- (5)
- (10)
- (2)
- (1)
- (6)
- (6)
- (7)
- (12)
- (1)
- (1)
- (39)
- (1)
- (12)
- (11)
- (4)
- (2)
- (2)
- (15)
- (15)
- (1)
- (1)
- (1)
- (2)
- (9)
- (3)
- (2)
- (1)
- (1)
- (3)
- (6)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (6)
- (5)
- (2)
- (1)
- (19)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (22)
- (22)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (22)
- (16)
- (6)
- (2)
- (1)
- (1)
- (2)
- (7)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (8)
- (17)
- (2)
- (1)
- (6)
- (1)
- (3)
- (1)
- (2)
- (1)
- (6)
- (2)
- (4)
- (2)
- (1)
- (1)
- (1)
- (6)
- (2)
- (3)
- (3)
- (3)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (5)
- (3)
- (1)
- (4)
- (12)
- (48)
- (1)
- (4)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (7)
- (9)
- (22)
- (30)
- (1)
- (1)
- (3)
- (2)
- (2)
- (4)
- (11)
- (5)
- (1)
- (1)
- (55)
- (6)
- (1)
- (7)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (6)
- (4)
- (15)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (10)
- (1)
- (17)
- (9)
- (1)
- (1)
- (2)
- (4)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (11)
- (13)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (10)
- (23)
- (1)
- (16)
- (2)
- (2)
- (1)
- (1)
- (2)
- (6)
- (3)
- (1)
- (1)
- (7)
- (11)
- (3)
- (2)
- (1)
- (1)
- (2)
- (4)
- (5)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (34)
- (3)
- (4)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (3)
- (5)
- (8)
- (4)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (17)
- (1)
- (13)
- (2)
- (3)
- (1)
- (5)
- (18)
- (1)
- (13)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (18)
- (11)
- (18)
- (1)
- (1)
- (3)
- (1)
- (17)
- (8)
- (6)
- (2)
- (2)
- (2)
- (2)
- (1)
- (4)
- (4)
- (1)
- (3)
- (2)
- (7)
- (11)
- (2)
- (2)
- (2)
- (4)
- (1)
- (8)
- (5)
- (6)
- (24)
- (2)
- (1)
- (2)
- (6)
- (1)
- (4)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (9)
- (12)
- (1)
- (12)
- (26)
- (8)
- (1)
- (1)
- (1)
- (7)
- (9)
- (1)
- (1)
- (1)
- (3)
- (1)
- (15)
- (5)
- (2)
- (2)
- (3)
- (4)
- (2)
- (1)
- (5)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (8)
- (6)
- (1)
- (2)
- (2)
- (7)
- (1)
- (1)
- (11)
- (8)
- (1)
- (3)
- (4)
- (1)
- (2)
- (6)
- (6)
- (2)
Percent Purity
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (1)
- (3)
- (6)
- (1)
- (5)
- (27)
- (2)
- (15)
- (4)
- (3)
- (9)
- (4)
- (4)
- (18)
- (8)
- (2)
- (4)
- (7)
- (1)
- (32)
- (2)
- (75)
- (1)
- (4)
- (53)
- (1)
- (3)
- (1)
- (10)
- (6)
- (33)
- (6)
- (1)
- (1)
- (106)
- (1)
- (9)
- (544)
- (5)
- (462)
- (42)
- (22)
- (130)
- (9)
- (1)
- (117)
- (1)
- (2)
- (3)
- (1)
- (1)
- (27)
- (32)
- (15)
- (4)
- (13)
- (12)
- (1)
- (2)
- (2)
- (13)
- (1)
- (2)
- (2)
- (1)
- (2)
- (20)
- (1)
- (1)
- (1)
- (1)
- (27)
- (6)
- (1)
- (1)
- (4)
- (5)
- (4)
- (5)
- (3)
- (1)
- (3)
- (1)
- (47)
- (1)
- (11)
- (364)
- (5)
- (3)
- (133)
- (1,015)
- (4)
- (2)
- (1)
- (3)
- (12)
- (904)
- (7)
- (35)
- (7)
- (2)
- (1)
- (418)
- (26)
- (4)
- (10)
- (1)
- (1)
- (4)
- (1)
- (2)
- (6)
- (2)
- (4)
- (1)
- (4)
Physical Form
- (1)
- (3)
- (19)
- (2)
- (8)
- (72)
- (4)
- (1,561)
- (2)
- (4)
- (12)
- (9)
- (1)
- (14)
- (3)
- (9)
- (3)
- (2)
- (5)
- (4)
- (2)
- (1)
- (16)
- (3)
- (13)
- (11)
- (13)
- (10)
- (2)
- (2)
- (1)
- (2)
- (2)
- (408)
- (5)
- (6)
- (2)
- (7)
- (2)
- (3)
- (2)
- (237)
- (3)
- (2)
- (3)
- (18)
- (5)
- (2)
- (264)
- (3)
- (4)
Boiling Point
- (4)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (2)
- (2)
- (5)
- (2)
- (3)
- (9)
- (2)
- (2)
- (2)
- (2)
- (2)
- (7)
- (1)
- (1)
- (2)
- (2)
- (8)
- (3)
- (2)
- (2)
- (5)
- (4)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (3)
- (3)
- (1)
- (2)
- (3)
- (13)
- (1)
- (2)
- (1)
- (4)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (9)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (10)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (5)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (3)
- (3)
- (4)
- (2)
- (1)
- (3)
- (3)
- (2)
- (3)
- (1)
- (1)
- (5)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (3)
- (6)
- (1)
- (4)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (4)
- (3)
- (6)
- (3)
- (1)
- (9)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (3)
- (1)
- (1)
- (2)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (2)
- (6)
- (2)
- (1)
- (1)
- (3)
- (9)
- (2)
- (1)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (3)
- (2)
- (6)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (5)
- (1)
- (2)
- (2)
- (3)
- (1)
- (3)
- (2)
- (3)
- (9)
- (4)
- (1)
- (4)
- (4)
- (1)
- (2)
- (3)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (7)
- (3)
- (2)
- (1)
- (2)
- (2)
- (5)
- (3)
- (1)
- (1)
- (3)
- (2)
- (1)
- (3)
- (1)
- (2)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (4)
- (2)
- (5)
- (1)
- (3)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (3)
- (3)
- (2)
- (2)
- (3)
- (3)
- (2)
- (1)
- (1)
- (2)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (4)
- (1)
- (3)
- (3)
- (2)
- (1)
- (4)
- (1)
- (1)
- (4)
- (4)
- (1)
- (4)
- (3)
- (6)
- (2)
- (2)
- (3)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (6)
- (3)
- (1)
- (5)
- (3)
- (4)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (4)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (3)
- (4)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (1)
- (3)
- (3)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
- (6)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (5)
- (3)
- (5)
- (2)
- (4)
- (4)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (7)
- (1)
- (3)
- (3)
- (4)
- (3)
- (3)
- (5)
- (6)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (4)
- (7)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (3)
- (3)
- (3)
- (4)
- (2)
- (3)
- (2)
- (2)
- (3)
- (2)
- (3)
- (1)
- (1)
- (2)
- (5)
- (1)
- (4)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (6)
- (1)
- (1)
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![Medchemexpress LLC Phenol, 4-[3-[1,3-dihydro-5-(methylsulfonyl)-2H-isoindol-2-yl]-3-methylbutyl]-2-(1,1-dimethylethoxy)- | 1802632-22-9 | 99.0% | 431.59 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000439515-Logo.png-250.jpg)
Medchemexpress LLC Phenol, 4-[3-[1,3-dihydro-5-(methylsulfonyl)-2H-isoindol-2-yl]-3-methylbutyl]-2-(1,1-dimethylethoxy)- | 1802632-22-9 | 99.0% | 431.59 | 25 MG
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Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Zervimesine (CT1812) is an orally active and brain penetrant sigma-2 receptor antagonist with a Ki of 8.5 nM. It can be used for the research of Alzheimer's disease. It has the potential for research in Alzheimer's disease, including the reversal and prevention of amyloid beta oligomer-induced vesicular membrane trafficking in Sprague-Dawley rat neurons.
- Orally active and brain penetrant sigma-2 receptor antagonist
- Ki of 8.5 nM for sigma-2 receptor
- Displaces and prevents Aβ oligomer binding in neurons and glia
- Increases synaptic number and protein expression in neurons
- Selectively reduces Aβ oligomer extracellular concentrations in transgenic hAPP/PS1 mice
- Improves cognitive performance in transgenic Thy1 huAPPSwe/Lnd+ male mice
- Appearance: Solid
- Color: White to off-white
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7,427
![Medchemexpress LLC 1H-pyrazolo[3,4-d]pyrimidine, 4-(1-azetidinyl)-1-methyl-3-[1-methyl-5-[4-(trifluoromethyl)phenyl] | 1415637-72-7 | 99.5% | 413.40 g·mol⁻¹ | C20H18F3N7 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000249033.png-250.jpg)
Medchemexpress LLC 1H-pyrazolo[3,4-d]pyrimidine, 4-(1-azetidinyl)-1-methyl-3-[1-methyl-5-[4-(trifluoromethyl)phenyl] | 1415637-72-7 | 99.5% | 413.40 g·mol⁻¹ | C20H18F3N7 | 5 MG
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PF-05085727 is a potent, selective, brain-penetrant inhibitor of cGMP-dependent phosphodiesterase 2A (PDE2A) with an IC50 of 2 nM. Supplied as research-grade material in solid form and as a DMSO solution, it is suitable for in vitro and in vivo studies of PDE2A signaling and CNS pharmacology.
- Potent PDE2A inhibition (IC50 = 2 nM).
- High selectivity: >4,000-fold versus PDE1 and PDE3-11.
- Brain penetrant, suitable for CNS pharmacology studies.
- Available as solid (5-200 mg) and 10 mM solution in DMSO.
- High chemical purity (~99.5%).
- Useful tool compound for studying cGMP signaling and PDE2A-related biology.
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7,428
Medchemexpress LLC TRITC-conjugated AffiniPure Goat Anti-Mouse IgG H&L | 100 UL
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TRITC-conjugated Goat Anti-Mouse IgG H&L is a TRITC-conjugated, goat-derived anti-mouse IgG antibody that conjugates the light and heavy chains of mouse IgG antibodies. It is supplied in PBS containing 50% glycerol, 0.5% BSA, and 0.02% sodium azide, with a pH of 7.3.
- Goat host
- Mouse reactivity
- TRITC conjugation
- Supplied in PBS containing 50% glycerol, 0.5% BSA, and 0.02% sodium azide
- Stable for 1 year when stored at -20°C
- Protect from light and avoid repeated freeze/thaw cycles
- Liquid appearance
- Recommended for ICC/IF applications at 1:100-1:1000 dilution
- Recommended for FC applications at 1:500-1:1000 dilution
- Ships with blue ice
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7,429
Medchemexpress LLC RGD peptide (GRGDNP) | 114681-65-1 | 99.83% | 614.61 | 50 MG
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RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. It competitively inhibits α5β1 binding with extracellular matrix (ECM) and promotes apoptosis through the activation of conformational changes that enhance pro-caspase-3 activation and autoprocessing. This peptide plays an important role in cell adhesion, migration, growth, and differentiation.
- Inhibits integrin-ligand interactions.
- Competitively inhibits α5β1 binding with extracellular matrix (ECM).
- Promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing.
- Important for cell adhesion, migration, growth, and differentiation.
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7,430
Medchemexpress LLC Immepip dihydrobromide | 164391-47-3 | MFCD06407876 | 99.9% | 327.06 | C9H17Br2N3 | 50 MG
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Immepip dihydrobromide is the dihydrobromide salt of immepip, a potent histamine H3 receptor agonist used in neuroscience research to probe H3-mediated modulation of histaminergic signaling. It has been reported to reduce cortical histamine release and is used to study neurological disease mechanisms.
- Potent histamine H3 receptor agonist suitable for receptor pharmacology studies.
- Reduces cortical histamine release in reported studies.
- High purity for research use (listed as 99.89%).
- Supplied as a crystalline dihydrobromide salt for experimental consistency.
- Available in multiple pack sizes, including 50 mg, for laboratory flexibility.
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7,431
Cayman Chemical 10Nitrooleated17
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An internal standard for the quantification of arachidonic acid by GC- or LC-MS
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7,432
Cayman Chemical AM1172 Fatty Acids and Derivat
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A hydrolysis-resistant endocannabinoid analog that inhibits AEA cellular uptake; resistant to FAAH hydrolysis; is the structurally “reversed” isomer of AM404; blocks the uptake of tritiated AEA (EC50 = ~1.5 µM in mouse cortical neurons)
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7,433
Medchemexpress LLC Monastrol | 329689-23-8 | MFCD11978057 | 292.35 g/mol | C14H16N2O3S | 5 MG
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Monastrol is a cell-permeable, allosteric inhibitor of the mitotic kinesin Eg5 (KIF11) used in cell biology and cancer research to induce mitotic arrest and study spindle dynamics. It produces monopolar spindles and exhibits antiproliferative effects in multiple cell lines.
- Selective inhibitor of the mitotic kinesin Eg5 (KIF11).
- Cell-permeable small molecule suitable for in vitro and cellular assays.
- Induces mitotic arrest characterized by monopolar spindles.
- Reported IC50 ≈ 14 μM against Eg5 ATPase activity.
- Supplied as a solid research reagent; common pack sizes include 1 mg, 5 mg, and 10 mg.
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7,434
Medchemexpress LLC Lerociclib | 1628256-23-4 | 98.4% | 474.60 | 25 MG
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Lerociclib | 1628256-23-4 | 98.4% | 474.60 | 25 MG
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7,435
Medchemexpress LLC Benzamide, N-(9,10-dihydro-9,10-dioxo-2-anthracenyl)- | 52869-18-8 | 99.4% | 327.33 | 1 ML
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This product is a Benzamide derivative identified as Benzamide, N-(9,10-dihydro-9,10-dioxo-2-anthracenyl)- with a CAS number of 52869-18-8 and a molecular weight of 327.33. It is supplied as a solid for laboratory and research applications.
- High purity of 99.4%
- Stable under recommended storage conditions
- Suitable for laboratory and research use
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7,436
Medchemexpress LLC ASN03576800 | 957513-35-8 | 99.6% | 285.27 | 1 ML
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ASN03576800 is a potent inhibitor for Ebola virus matrix protein VP40, which plays a role in viral assembly and budding processes. It functions by occupying the RNA binding region of VP40.
- Potent inhibitor for Ebola virus matrix protein VP40.
- Occupies the RNA binding region of VP40.
- Intended for research use only.
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7,437
Cambridge Isotope Laboratories 1 2 3 6 7 8-HexaCN (PCN-70) (unlabeled) 100 ug/mL in nonane CP 97% 1 mL
1 2 3 6 7 8-HexaCN (PCN-70) (unlabeled) 100 ug/mL in nonane CP 97% 1 mL
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7,438
Medchemexpress LLC trans-Nerolidol | 40716-66-3 | 50 MG
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trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (DOX) against intestinal cancer and breast cancer cells in vitro. It increases the accumulation of DOX inside cells in vitro and activates apoptosis in vivo.
- Improves the anti-proliferative effect of doxorubicin (DOX) against intestinal cancer and breast cancer cells in vitro.
- Increases accumulation of doxorubicin (DOX) inside cells in vitro.
- Activates apoptosis in vivo.
- Purity: 96.24%
- Appearance: Liquid (density: 0.869±0.06 g/cm3)
- Color: Colorless to light yellow
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7,439
Medchemexpress LLC S-oxiracetam | 88929-35-5 | MFCD00242951 | 99.6% | 158.16 g/mol | C6H10N2O3 | 100MG
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S-oxiracetam is the S-enantiomer of oxiracetam, a racetam-family nootropic research compound used in neuroscience and neuroprotection studies. Supplied as a high-purity research chemical in solid and solution formats for laboratory applications.
- High purity suitable for analytical and in vitro research.
- Available in multiple pack sizes, including solid and DMSO solution formats.
- Recommended storage: sealed at 4°C; specific solvent storage guidelines apply.
- Characterized by CAS 88929-35-5 and molecular weight 158.16 g/mol.
- Synonyms include (S)-(-)-oxiracetam and (S)-ISF2522.
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7,440
Medchemexpress LLC Hydrangenol | 480-47-7 | 1 MG
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Hydrangenol is an orally active antiphotoaging compound isolated from Hydrangea serrata leaves. It prevents wrinkle formation by reducing MMP and inflammatory cytokine expression, and by increasing moisturizing factors and antioxidant gene levels.
- Reduces wrinkle formation, dorsal thickness, dehydration, and collagen degradation
- Increases expression of involucrin, filaggrin, and aquaporin-3 (AQP3)
- Promotes hyaluronic acid (HA) production
- Decreases matrix metalloproteinase (MMP)-1/-3, cyclooxygenase-2 (COX-2), and interleukin-6 (IL-6) expression
- Attenuates phosphorylation of MAPKs (ERK and p38)
- Upregulates Nrf2, HO-1, NQO-1, GCLM, and GCLC expression
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